设为首页 繁体中文  
您现在的位置: 安徽省宿城第一中学 > 校友会 > 校友风采 > 正文
87届校友刘海燕简介
作者:佚名    文章来源:本站原创    点击数:2475    更新时间:2015-8-27         ★★★

 

刘海燕,教授,博士生导师。1990年本科博士毕业于中国科学技术大学生物系。1996年博士毕业于中国科学技术大学,获郭沫若奖。1993-1995年作为联合培养研究生在瑞士苏黎世高等理工学院物理化学实验室学习。1998-2000年在杜克大学和北卡罗来纳大学博士后。现为我校生命科学学院教授、博士生导师。在生物分子计算机模拟与设计方法和酶催化模拟领域发表研究论文六十余篇。2000年入选中国科学院引进国外杰出人才项目。2001年获国家杰出青年基金资助。2004年获安徽省青年科技奖。

实验室主页:http://biocomp.ustc.edu.cn/ 

 

主要研究兴趣

1) 蛋白质空间结构和动力学的计算机模拟方法与应用;

2) 蛋白质设计理论与实验方法及其在合成生物学中的应用。

 

近期代表性论文:

1. Wei Zhao, Meng Xu, Zhi Liang, Bo Ding, Liwen Niu, Haiyan Liu*, and Maikun Teng*, Structure-based de novo prediction of zinc-binding sites in proteins of unknown function, Bioinformatics 2011 27: 1262-1268.

2. Jian Zhan, Bo Ding, Rui Ma, Xiaoyu Ma, Xiaofeng Su, Yun Zhao, Ziqing Liu, Jiarui Wu, Haiyan Liu*, Develop Reusable and Combinable Designs for Transcriptional Logic Gates, Mol Syst Biol 2010,6:388.

3. Quan Li, Changhai Zhou, Haiyan Liu*, Fragment-based local statistical potentials derived by combining an alphabet of protein local structures with secondary structures and solvent accessibilities. Proteins. 2009, 74, 820-36.

4. Zanxia Cao, Haiyan Liu*; Using free energy perturbation to predict effects of changing force field parameters on computed conformational equilibriums of peptides; J Chem Phys, 2008, 129, 015101.

5. Cao Xu, Jun Wang, Haiyan Liu*, A Hamiltonian replica exchange approach and its application to the study of side chain type and neighbor effects on peptide backbone conformations, J Chem Theor Comput, 2008,4,1348-1359.

6. Jun Wang, Yan Gu, Haiyan Liu*; Determination of conformational free energies of peptides by multidimensional adaptive umbrella sampling; J Chem Phys 2006,125, 094907.

7. Sanmei Cheng, Yuedong Yang, Wenrui Wang, Haiyan Liu*; Transition State Ensemble for the Folding of B Domain of Protein A: A Comparison of Distributed Molecular Dynamics Simulations with Experiments; J Phys Chem B. 2005,109, 23645-23654.

8. Li Xie, Haiyan Liu*, Yang Weitao*; Adapting the nudged elastic band method for determining minimum-energy paths of chemical reactions in enzymes, J Chem Phys, 2004, 120,8039.

9. Jiang Zhu, Qianqian Zhu, Yunyu Shi and Haiyan Liu*; How Good can we predict native contacts in proteins based on decoy structures and their energies? Proteins, 2003,52, 598.

10. Zhiyong Zhang, Yunyu Shi*, and Haiyan Liu*; Molecular dynamics simulations of peptides and proteins with amplified collective motions, Biophys J, 2003, 84, 3583.

 

 

 

 

文章录入:xyh    责任编辑:xyh 
发表评论】【加入收藏】【告诉好友】【打印此文】【关闭窗口
  • 上一篇文章:
  • 下一篇文章:
  •    网友评论:(评论内容只代表网友观点,与本站立场无关!
    数据载入中,请稍后……

     

    | 设为首页 | 加入收藏 | 联系站长 | 友情链接 | 版权申明 | 网站公告 |
    版权所有:Copyright? 2013 宿城一中 Powered by:scyz Ver3.51 学校投诉电话:0557-3917805 维护:信息中心